Role of Oxidative Stress in Polycystic Ovary Syndrome

Authors

  • Afsharian, Parvaneh Department of Genetics, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran
  • Hashemian, Zohreh Department of Genetics, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran
Abstract:

Introduction: Polycystic ovary syndrome is one of the most common causes of infertility. 6 to 8 percent of women of childbearing age have this endocrine disorder. Biochemical abnormalities in these patients lead to imbalance of female hormones and increased androgens, which can have consequences such as menstrual cycle disorder, hirsutism, acne vulgaris and androgenic alopecia. Despite the long history of studies on polycystic ovary syndrome, the cause is still unknown. Oxidative stress is an imbalance between the production of reactive oxygen species and the amount of antioxidant. When this balance is disturbed, the result is an increase in the level of oxidative stress. Oxidative stress is currently recognized as one of the major pathophysiologies of many disorders and diseases, including polycystic ovary syndrome. Understanding the mechanisms of oxidative stress is crucial for developing strategies for the prevention and treatment of this disease. In this article, we reviewed the data on the mechanism of oxidative stress in polycystic ovary syndrome.  

Upgrade to premium to download articles

Sign up to access the full text

Already have an account?login

similar resources

Roles of Oxidative Stress in Polycystic Ovary Syndrome and Cancers

Oxidative stress (OS) has received extensive attention in the last two decades, because of the discovery that abnormal oxidation status was related to patients with chronic diseases, such as diabetes, cardiovascular, polycystic ovary syndrome (PCOS), cancer, and neurological diseases. OS is considered as a potential inducing factor in the pathogenesis of PCOS, which is one of the most common co...

full text

Role of Gut Microbiome in Polycystic Ovary Syndrome

 Polycystic ovary syndrome (PCOS) is a complex endocrine disorder that affects 8-13% of women at reproductive age worldwide. This disorder is usually associated with menstrual disorders, infertility, obesity, and insulin resistance. The underlying cause of this syndrome is unknown, however in recent years, researchers have shown an association between intestinal microbiota alterations )dysbiosi...

full text

Polycystic ovary syndrome. Polycystic ovary syndrome.

If you get the printed book in on-line book store, you may also find the same problem. So, you must move store to store and search for the available there. But, it will not happen here. The book that we will offer right here is the soft file concept. This is what make you can easily find and get this polycystic ovary syndrome polycystic ovary syndrome by reading this site. We offer you the best...

full text

Relationship between Serum Levels of Anti-Mullerian Hormone, Adiponectin and Oxidative Stress Markers in Patients with Polycystic Ovary Syndrome

Background: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of reproductive age. Anti-Mullerian hormone (AMH) is a valid indicator of ovarian function and is used for PCOS diagnosis. Some studies have shown that adipokines affect the synthesis of AMH, and therefore they are somehow related in function. The aim of the present study was to determine the relationshi...

full text

Role of oxidative stress in pathogenesis of metabolic syndrome

The metabolic syndrome (MS) recognized as a major cause of type 2 diabetes and cardiovascular diseases, has become one of the major public health challenges worldwide. The pathogenesis of the metabolic syndrome is multiple and still poorly understood. No single factor has yet been identified as an underlying causal factor. There is a growing belief, however, that obesity, specially visceral obe...

full text

My Resources

Save resource for easier access later

Save to my library Already added to my library

{@ msg_add @}


Journal title

volume 28  issue 5

pages  2635- 2647

publication date 2020-07

By following a journal you will be notified via email when a new issue of this journal is published.

Keywords

No Keywords

Hosted on Doprax cloud platform doprax.com

copyright © 2015-2023